14. July 2015

Telmisartan is poorly soluble in water, and the rate of dissolution, as well as bioavailability, is less. In the present study, an attempt has been made to improve the dissolution of the drug by coating the drug and carrier over sugar pellets. The solubility promoters such as alkalizes, binders and surfactants were selected to make the drug solution. The prepared pellets were evaluated for their physicochemical properties and in-vitro dissolution. The drug release rate was found to be more from...