07. April 2016

Aim: To develop and evaluate interpolymer complex based buccal mucoadhesive films of Tramadol Hydrochloride. The interpolymer complex was prepared by using Chitosan and Aloe vera gel mucilage. Materials and Methods: In present study the inter polymer complex is formed between mucoadhesive polymer chitosan and aloe vera gel mucilage. The resulted interpolymer complex is used to prepare buccal mucoadhesive films of Tramadol Hydrochloride, an opioid analgesic. Other excipients includes glycerin as...