16. May 2016

The development of Garlic as a commercial antibiotic has come to a halt. Although its efficiency is scientifically proven; it has only been used as dietary supplement or as traditional medicine. In this study we investigated the use of spray drying to obtain a powder which releases allicin, the most important antibiotic active compound in garlic. Alliin and alliinase, which serve as precursors for allicin production, were encapsulated separately into microspheres consisting of lactose as a...

20. March 2016

This work describes an approach to modify the release of active compound from a 3D printed model drug product geometry intended for flexible dosing and precision medication. The production of novel polylactic acid and hydroxypropyl methylcellulose based feed materials containing nitrofurantoin for 3D printing purposes is demonstrated. Nitrofurantoin, Metolose® and polylactic acid were successfully co-extruded with up to 40% Metolose® content, and subsequently 3D printed into model disk...