04. April 2017
Abstract The objective of this study was to prepare and evaluate some physiochemical and biopharmaceutical properties of bitter taste masking microparticles containing azithromycin loaded in dispersible tablets. In the first stage of the study, the bitter taste masking microparticles were prepared by solvent evaporation and spray drying method. When compared to the bitter threshold (32.43 µg/ml) of azithromycin (AZI), the microparticles using AZI:Eudragit L100 = 1:4 and having a size...
24. March 2016
Objective: The main objective of this review is to investigate the potential role of milk in improvement of bioavailability and patient compliance. Method: The study reviews the types of milk based on its composition, mechanism of how milk improves the solubility of poorly soluble drugs, masks the taste of bitter drugs and improves the patient compliance to dosage regimen. It also reviews various research studies done so far that recommend the use of milk in formulations. Along with this, the...
