28. December 2016
Aim: The main objective of the present investigation was to formulate and characterize an oral pulsatile drug delivery system of flurbiprofen, for time dependent release, based on chronomodulated approach for the management of rheumatoid arthritis. Settings and Design: The drug delivery system was designed to deliver the drug with a lag time to release the drug when it could be most needful to patients of rheumatoid arthritis. Materials and Methods: Rapid release core tablets of flurbiprofen...
18. October 2016
ABSTRACT The goal in drug delivery research is to meet therapeutic needs relating to particular pathological conditions by developing new formulations. Research in the chronopharmacological field has demonstrated the importance of biological rhythms in drug therapy, and this has brought a new approach to the development of oral drug delivery systems. Chronotherapeutics is the discipline concerned with the delivery of drugs according to the intrinsic activities of a disease over a certain period...
