31. August 2018
The main objective of the presented research was to prepare an innovative carrier as a filler for detection tubes in the form of double-coated pellets with a very significant color transition during the detection of cholinesterase inhibitors such as nerve agents, organophosphorus or carbamate insecticides in liquids that is observable visually and also spectrophotometrically at 412 nm. The pellet cores were prepared by the extrusion/spheronization method. Consecutively, two different coats...
08. August 2018
The main purpose of this study was to investigate the influence of ethylcellulose (EC) coating and curing conditions on the quality attributes of pharmaceutical pellets prepared using a quality by design (QbD) approach. The drug release rate of methimazole, a freely soluble model drug, was evaluated extensively together with the mechanical strength and true density of the coated pellets. Moreover, the thermal and spectroscopic properties, as well as the surface characteristics were studied...
10. July 2018
In a joint initiative, Ideal Cures - India's foremost film-coating and pharmaceutical excipient company - along with Express Pharma, India's leading pharmaceutical and biotechnology publication, in their endeavor to recognize and appreciate FR&D scientists conceptualized, initiated and sponsored the 'Formulation and Drug Delivery Leadership Awards' at the Formulation and Drug Delivery (FDD) Conclave 2018. In its second year, FDD Leadership Awards held on 15 June 2018, Hyderabad, saw over...
04. July 2018
Global trade means that extra effort is required to protect one's products from the manufacturing line through distribution to the point of sale. In particular, it is not enough to track and trace packaged products throughthe supply chain using printed unique product identifiers and serialization systems, because new serialization requirements in many countries also require proof that the contents of the packages are actually genuine (authentic) and can be authenticated easily. This leaves...
17. June 2018
For decades, TiO2 is used as a white pigment due toits very high opacity and brightness. Therefore, it has a wide range of applications, from colouring ingredient of pharmaceutical film coating, to food application colouring.
On the basis of current discussions on a new classification and labelling of TiO2 and EFSA’s re-evaluation of TiO2 (E171) as a food additive, BIOGRUND is committed to offer alternatives for common film coating formulations.
10. June 2018
The focus of the OSeeT are enteric coatings (EC) and modified-release (MR) coatings. The characteristics of the coating layer are revealed via OSeeT: Mean coating thickness → progress of coating process Intra-particle and inter-particle coating variability → for quality and homogeneity of the applied coating Roughness → optical quality of the surface The Technology behind OSeeT is Interferometry OCT is based on white light interferometry: – broad bandwidth resulting in low-coherence...
18. May 2018
The European Food Safety Authority (EFSA) will advise the Commission on whether to re-evaluate titanium dioxide by analysing four scientific studies that questioned the additive's safety. Article from Foodnavigator.com
16. May 2018
Do you need a tablet film coating with natural colors and TiO2-free? Pharmaexcipients.com offers the access to the film coating experts. They put together a tailored ready to use coating based on your application in a fast and simple way. Just fill in the questionnaire and you will get a free sample.
15. May 2018
Asolventless process for simultaneously milling and dry coating microcrystalline cellulose (MCC) was investigated for producing fine excipients in five different sizes (∼20, 25, 30, 35, 40µm) havinghigh bulk density (BD), good flow function coefficient (FFC), and excellent compaction. Avicel PH-102, used as the starting material, was milled and coated with two grades of silicas, hydrophobic andhydrophilic (R972P and A200), using a fluid energy mill (FEM). Through judicious selection of the...
25. April 2018
Parenteral sustained release systems for proteins which provide therapeutic levels over a longer period avoiding frequent administration, which preserve protein stability during manufacturing, storage and application and which are biodegradable and highly biocompatible in the body are intensively sought after. The aim of this study was to generate and study mannitol core microparticles loaded with a monoclonal antibody IgG1 and coated with lipid either hard fat or glyceryl stearate at different...