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24. September 2017
Objective: The aim of present study was to prepare and evaluate the trans- dermal lms (TFs) of Nifedipine (NFDP). Methods: The TFs were prepared by solvent evaporation technique and twelve formulations of NFDPTFs were prepared by taking HPMC E15 and Eudragit L100 in different ratios. Polyethylene glycol (15%) and Dimethyl sulfoxide (DMSO) were incorpo- rated as plasticizer and permeation enhancer respectively. DMSO was in- corporated in the formulations F7-F12 but it was absent in F1-F6....