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22. September 2016
Surface energies and dynamic vapour sorption (DVS) plays an imparative role in drug polymer interaction in the formulation development for a number of applications. Powdered films of two pH sensitive polymers namely hypromellose phthalate (HPMCP) and methacrylic acid copolymer NF (Eudragit L30-55) were studied for surface energy analysis employing inverse-phase gas chromatography (IGC) which is a well-known physi- cal technique in acquiring significant information about surfaces of...
24. September 2015
The article describes the application of a twin-screw granulation process to enhance the dissolution rate of the poorly water soluble drug, ibuprofen (IBU). A quality-by-design (QbD) approach was used to manufacture IBU loaded granules via hot-melt extrusion (HME) processing. More