19. May 2016

In the present investigation, liquisolid compact technique is investigated as a tool for enhancement of dissolution of poorly water-soluble drug, Deflazacort. Deflazacort liquisolid tablets were prepared using propylene glycol as non-volatile liquid vehicle, microcrystalline cellulose (Avicel PH 102) as carrier material, colloidal silicon dioxide (Aerosil 200) as coating material and sodium starch glycolate as super disintegrant. The prepared liquisolid compacts were evaluated for bulk density,...