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12. October 2017
The current study was designed for preparation of gastro-retentive floating tablet of ranitidine HCl by using polymers ethyl cellulose (EC) and hydroxypropyl methylcellulose and xanthan gum (XG) in an attempt to delay its gastric retention time. The tablets were manufactured by direct compression technique. The outcome of varying concentrations of HPMC, XG and EC on drug release was evaluated.