Posts tagged with "Everted"



24. October 2016
Purpose Desvenlafaxine succinate (DSV) is a water soluble anti-depressant drug, which is rapidly absorbed after oral administration exaggerating its side effects. The current work aims to prepare controllable release DSV matrix to reduce DSV side effects related to its initial burst. Methods Fifteen DSV matrix formulations were prepared using different polymers, polymer/drug ratios and matrix excipients and characterized using Differential Scanning Calorimetry (DSC), infra-red (IR)...
14. November 2015
Highlights • Cilostazol has low oral bioavailability due to poor aqueous solubility. • Cilostazol was loaded in nanoemulsion formulations. • Developed formulation possessed good physical stability. • Drug loaded nanoemulsion enhances permeation of drug through membrane. • Nanoemulsion showed increase in oral bioavailability of drug. More