17. January 2018
Controlled release dosage forms are essential in certain dosage regimens where release rate of drug impacts the effectiveness for therapy. In the present study, modified release dosage form of Domperidone was developed in the form of pellets which were subsequently compressed into tablet to disintegrate and swallow by patients without changing the release profile.
01. November 2017
A two factor three level factorial design was used to investigate the effects of carbopol and cationic hydrophilic polymerswhich have a common use in buccal drug formulations. Statistical modelswith interaction terms were derived to evaluate influence of carbopol(X1) and chitosan (X2) on tablet disintegration (Y1) and dissolution(Y2), mechanical properties (Y3), swelling (Y4).
12. October 2017
Nowadays micro- and nanotechnologies have emerged as one of the most promising strategies in the pharmaceutical practice to achieve site-speci c and controlled drug delivery.1 Biodegradable mic- roparticles have been extensively utilised for oral and parenteral administration, and recently they have also been considered as an approach to deliver drugs nasally