25. April 2018
Parenteral sustained release systems for proteins which provide therapeutic levels over a longer period avoiding frequent administration, which preserve protein stability during manufacturing, storage and application and which are biodegradable and highly biocompatible in the body are intensively sought after. The aim of this study was to generate and study mannitol core microparticles loaded with a monoclonal antibody IgG1 and coated with lipid either hard fat or glyceryl stearate at different...
11. January 2017
Purpose The objectives of this study were to develop once-a-day oral controlled-release tablets of quetiapine fumarate (QF) and to determine the effect of polymer type, viscosity grade, polymer ratio, and polymer rheological properties on the rate of QF release from hydroxypropyl methylcellulose (HPMC) matrix tablets. More
12. November 2015
The aim of current research was to develop and characterize solid self-emulsified nanostructures (S-SEN) loaded with a BCS class II drug, Lercanidipine hydrochloride (LCH). The liquid self-emulsified nanostructures (L-SEN) were prepared using rice bran oil and glyceryl monooleate (GMO) as oil phase and Tween 80 and propionic acid as surfactant and co-surfactant respectively. More