27. August 2018

Affinisol® (Hydroxypropylmethyl cellulose) polymers with low glass-transition temperature are usually processed by Melt Extrusion and show better compressibility at lower compression pressure. This study evaluates the compaction properties and powder properties of Affinisol® Powder by the determination of physical properties like bulk/tapped density, angle of repose and loss on drying, an out-of-die compactability, axial expansion post-compression, effect of compression force on hardness of...

15. March 2018

Salts of weakly basic active pharmaceutical ingredients are widely used to improve aqueous solubility and/or dissolution rate. However, these compounds are prone to precipitation due to the lower solubility of the un-ionized species at the higher pH in the intestinal region, and this can result in poor and/or variable absorption.

07. February 2018

Polymeric hydrogels are common dosage forms designed for the topical administration of antimicrobial drugs to treat vaginal infections. One of the major advantages of using chitosan in these formulations is related to the intrinsic and broad antimicrobial activity exerted on bacteria and fungi by this natural polymer. Most vaginal yeast infections are caused by the pathogenic fungus Candida albicans.