18. October 2017
In the drug delivery area, versatile therapeutic systems intended to yield customized combinations of drugs, drug doses and release kinetics have drawn increasing attention, especially because of the advantages that personalized pharmaceutical treatments would offer.
26. March 2016
The objective of the present study was to develop a one-step process for the production of tablets directly from primary powder by means of injection molding (IM), to create solid-dispersion based tablets. Fenofibrate was used as the model API, a polyvinyl caprolactame-polyvinyl acetate-polyethylene glycol graft co-polymer served as a matrix system. Formulations were injection-molded into tablets using state-of-the-art IM equipment. The resulting tablets were physico-chemically characterized...
11. May 2015
The objective of this doctoral thesis was to evaluate the use of several non-conventional polymers as matrix excipients for hot melt extruded oral-release formulations. Expanding the range of polymers currently used for HME/IM could potentially solve the problems associated with the current formulations: pH dependent release profiles, stability issues, and low drug loaded dosage forms... https://biblio.ugent.be/publication/5947095 Bart Claeys UGent (2015)