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19. September 2015
A clinical studywas conducted to validate the in vivo drug release performance of IntelliCap® CR capsules.12 healthy, male volunteers were administered IntelliCap® CR capsules, filled with metoprolol as a BCS 1 model drug, and programmed to release the drug with 3 different release profiles (2 linear profiles extending over 6 h and 14 h, respectively, and a pulsed profile with two equal pulses separated by 5 h) using a cross-over design. More