02. June 2016
In this study, osmotically controlled drug delivery system of Nifedipine using different polymers were formulated. Nifedipine, is an anti-hypertensive drug. It acts as a calcium channel blockers. Unlike any other conventional dosage forms in osmotic system, the mechanism involved is osmosis. In the present studies, the release of the drug is porosity.A total of nine formulations were prepared by using the different polymers (Poly Ethylene oxide, HPMC K15 M and Ethyl cellulose) in different...
02. May 2016
Unraveling the mechanisms of nanoparticle transport across the intestinal barrier is essential for designing more efficient nanoparticles for oral administration. The physicochemical parameters of the nanoparticles (e.g., size, surface charge, chemical composition) dictate nanoparticle fate across the intestinal barrier. This review aims to address the most important findings regarding polymeric and lipidic nanoparticle transport across the intestinal barrier, including the evaluation of...