18. September 2016

Abstract: Background: Amphotericin B eye drops are widely used in the treatment of ocular infections. However, amphotericin’s toxicity leads to low patient compliance and aggravation of symptoms. This work describes the development of a microemulsion system containing amphotericin B, aiming for its use in ocular applications. Methods: The microemulsion was developed by the titration technique. The physicochemical characteristics were determined with both loaded and unloaded amphotericin...

19. September 2015

The development of new more effective therapeutic treatments for pain relief is essential for enhancing the patient quality of life and safety and avoiding or limiting risks of abuse, addiction or serious injuries posed by some of the present pain therapies. More