04. June 2016

In this study, potassium chloride (KCl) containing matrix pellets were compressed into tablets using powder or pellet form of partially spray dried lactose as filler-binder excipient. The spatial distribution of potassium chloride pellets within the tablets was examined by non-destructive microfocus X-ray imaging (MFX) and image analysis technique. The KCl content of the tablets was determined by conductivity measurement and these values were compared to the average gray values of the MFX...