18. August 2018

In contrast to classic single-unit dosage forms such as tablets, the dosage of the drug substance in multi-particulate systems is divided on a plurality of subunits – typically consisting of thousands of spherical pellet particles with a diameter of between 100 and 2,000 μm. This means that non-disintegrating, monolithic single-unit forms retain their structure in the digestive tract, whereas the multi-particular preparations consist of numerous sub-units which disperse after administration....

18. August 2018

Older adults with multimorbidity, polypharmacy, and complex health needs are the major consumer of health care. Ensuring that medicines are used safely, effectively, and delivered efficiently in this population is challenging. In this context, the approach to medicines delivery should seek to overcome some of the difficulties of delivering medicines to older people, and ensure each medication is delivered by the optimal and most convenient route for the patient in question. However, this poses...

15. March 2018

presented by Glatt @ 11th Worldmeeting on on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology -19 March to 22 March 2018 Granada, Spain On the Glatt Booth N° 3 we will exhibit our smallest continuous granulation line and inform about our solutions in micropellets, taste masking, pediatric formulation, drug delivery, etc. From our Pharmaceutical Development origin the following poster contributions: Influence of polymer content on droplet size distributions in atomized spraying...

04. March 2018

With manufacturers beginning to improve their understanding of the uses of multiparticulate products, alongside more research and progressive advancements being made, the future looks bright for pelletisation as a technique in drug development. Here, Dr Beata Vladovicova talks about the wide-ranging advantages of pelletisation, whilst also exploring the use of extrusion-spheronisation to produce these types of drugs. She also discusses the challenges faced in the development of pellets and why s

11. July 2017

Die Renaissance der Pellets treibt innovative Technologien voran. Formulierungen, die auf Pellets basieren, liegen in den letzten Jahren im Trend. Neue Technologien ermöglichen es, Schutzrechte an Wirkstoffen zu umgehen und stehen bei den Pharmakunden deshalb hoch im Kurs. Welches sind die wichtigsten Verfahren?

26. October 2016

Abstract The multiparticulate drug product concept covering micropellets, pellets, and mini-tablets is presented as a highly feasible approach to present convenient and patient friendly medication for the geriatric population. Improved swallowability and optimized administration regimen going along with defined drug dosage are achievable. Extemporaneous preparation of medicines from standard medication can be avoided going along with improved patient safety. With one multiparticulate pellet,...