20. February 2016

Extrusion spheronization is the widely used method by which the pellets are formulated. Pellets have certain advantages in the development of modified release dosage forms, Because of their regular shape and size they are suitable for coating and encapsulation processes, In addition, pellets may sometimes improve the bioavailability, reduce the risk of dose dumping and decrease local irritations in the gastrointestinal tract. Ideal pelletizing aid for this process is MCC as it possesses...