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16. March 2017
Abstract It is one of the best pharmaceutical dosage forms for those patients, they cannot take medicaments orally. Transdermal drug delivery system (TDDS) established itself as an integral part of novel drug delivery systems (NDDS). On the application of Transdermal patches, the delivery of the drug across dermis gives the systemic effect. TDDS is costly alternative to conventional formulation. It is also important due to its unique advantage. Controlled absorption, more uniform plasma levels,...
09. February 2017
ABSTRACT Objective: Transmucosal buccal drug delivery could be an alternative for oral administration for systemic delivery of Verapamil Hydrochloride (VH), as it has low bioavailability 20 - 35 % due to its extensive rst pass metabo- lism and variable absorption at GIT. Method: Buccal patches of VH were prepared by solvent casting method using bioadhesive polymers HPMC K4M, Carbopol 934P, Chitosan acetate and Okra mucilage isolated from Hibiscus esculantus fruits, in various combinations as...