14. February 2018
Solid oral dosage forms (SODF) are drug vehicles commonly prescribed by physicists in primary and secondary cares, as they are the most convenient for the patient and facilitate therapy management. Concerns regarding unintended adhesion of SODF during oro-esophageal transit remain, especially in multimorbid patients, bedridden patients and patients suffering from dysphagia.
06. November 2017
The aim of this study was to improve the pharmaceutical properties of theobromine (TB), particularly its flowability and dissolution rate, by preparing solid dispersions using different technologies (hot melt extrusion—HME, freeze-drying—FD, and supercritical fluid—SF) as well as testing different hydrophilic polymeric matrixes (Eudragit™ E, Plasdone™ S and Soluplus™)
22. November 2016
INTRODUCTION In recent years, the use of 3D printing (3DP) for formation of custom dose forms has received increasing research interest for pharmaceutical applications. To date limited API loadings have been achieved. Current fused deposition modelling (FDM) approaches utilise a formulated filament (e.g. polymer and active) as a feedstock which can be made by hot-melt extrusion (HME). One key purpose of this work is to explore methods of achieving developing a viable routes to establishing...