Posts tagged with "Rounding"


07. May 2015

Stages in spheronisation: Evolution of pellet size and shape during spheronisation of microcrystalline cellulose-based paste extrudates

•Tests with coloured pastes show that fines do not attach preferentially at pellet waist. •New ‘dumb-bellity’ measure to quantify the formation of dumb-bells •Spheronisation time increases with mass of charge until overmassing occurs. •Tests with calcium carbonate as model API exhibit the same behaviour. http://www.sciencedirect.com/science/article/pii/S003259101400864X

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