11. September 2018
Oromucosal drug delivery is necessary when a local effect in the oral cavity is required. Bioadhesive formulations should be advantageous because a larger fraction of the active principal is retained at the site of action allowing for an enhanced and prolonged effect. Despite a variety of mucoadhesion test systems being described in literature, none of these in-vitro tests does relate to physiological conditions in the oral cavity and suites for the testing of complete dosage forms, e.g....
10. July 2016
We previously prepared and pharmaceutically evaluated ginger orally disintegrating (OD) tablets, opti- mized the base formulation, and carried out a clinical trial in healthy adults in their 20s and 50s to measure their effect on salivary substance P (SP) level and improved swallowing function. In this study, we conducted clinical trials using the ginger OD tablets in older people to clinically evaluate the improvements in swallow- ing function resulting from the functional components of the...