27. July 2016

Granules with release-sustaining properties were developed by twin screw hot melt granulation (HMG) using a combination of stearic acid (SA) and high molecular weight polyethylene oxide (PEO) as matrix for a highly water soluble model drug, metoprolol tartrate (MPT). Earlier studies demonstrated that mixing molten SA and PEO resulted in hydrogen bond formation between hydroxyl groups of fatty acid molecules and ether groups in PEO chains. These molecular interactions might be beneficial in...

02. March 2016

Aim: To evaluate possible interaction between apple cider vinegar (ACV) which is the most frequent used active ingredient of diet pills with 20 different excipients. Materials and Methods: The pure drug ACV and drug-excipient powder mixtures which were stored under the condition of 40°C and 75% relative humidity for a period of 21-day and interaction were seen by using modern instrumental technique high-performance liquid chromatography, Fourier transmission infrared and differential scanning...

10. January 2016

06. October 2015