18. April 2016

The purpose of this study was to evaluate efficiency of fenugreek gum for developing gastro retentive floating tablets of Sumatriptan succinate when used alone or in combination with established polymers. The floating Tablet were prepared by direct compression and wet granulation technique and evaluated for various parameters like physical characterization, hardness, friability, weight variation, drug content uniformity, swelling index and in-vitro buoyancy and drug release. Fenugreek gum was...

09. April 2016

Sumatriptan succinate (SS) is a selective serotonin receptor agonist used for the treatment of migraine attacks, suffering from extensive first-pass metabolism and low oral bioavailability (∼14%). The aim of this work is to compare the performance of different ready-made co-processed platforms (Pharmaburst®, Prosolv ODT®, Starlac®, Pearlitol Flash®, or Ludiflash®) in the formulation of SS sublingual orodispersible tablets (ODTs) using direct compression technique. The prepared SS ODT...

09. March 2015

Dr. R. Srinivasan1, Sk. Shakir Ahmad1*, D. SK. Sarma1, D. Rajesh Kumar1, Dr. K. Ravi Kumar2, V. Mahesh Swami1 1Siddhartha Institute of Pharmaceutical Sciences, Jonnalagadda, Narsaraopet, Guntur, A.P, India 2Assosciate Professor, Hindu college of Pharmacy, Guntur, Andhra Pradesh, India Received 28 September 2014, Accepted 28 November 2014, Available Online 10 February 2015 Int. J. Med. Pharm. Res., 2015, 3(1): 937-941 http://www.pharmaresearchlibrary.com/wp-content/uploads/2015/02/IJMPR2405.pdf