31. March 2018
The growing popularity of direct-compression process necessitates an ideal filler–binder that can substitute two or more excipients. Pregelatinization of starches significantly improves swelling and flow properties but produces tablets with low mechanical strength.
12. October 2017
The current study was designed for preparation of gastro-retentive floating tablet of ranitidine HCl by using polymers ethyl cellulose (EC) and hydroxypropyl methylcellulose and xanthan gum (XG) in an attempt to delay its gastric retention time. The tablets were manufactured by direct compression technique. The outcome of varying concentrations of HPMC, XG and EC on drug release was evaluated.