23. April 2016

Multiparticulate dosage forms consist of small sub-units containing the drug and having the advantage of more uniform and predictable transit time, better distribution and less local irritation in the gastrointestinal tract, compared to single unit dosage forms [1, 2]. These multiparticulates, when designed as mucoadhesive formulations, can potentially prolong and normalize the residence time in the gastrointestinal tract, and increase oral drug bioavailability due to their adhesive...