20. April 2016
Extended release of drugs is extremely essential for patients who require medicinal treatment round the clock. Depressed patients are one of such patients who suffer from recurrent and chronic disorder requiring long-term treatment. The treatment for such disease lies in the use of anti-depressants. Venlafaxine hydrochloride (VF) is an effective third generation drug which is capable of inhibiting the reuptake of serotonin, norepinephrine and dopamine. This highly water soluble drug (534 mg/mL)...
07. April 2016
The oral route is considered as the most promising route of drug delivery. Effective oral drug delivery may depend upon the factors such as gastric emptying process, G I transit time of dosage form, drug release from the dosage form and site of absorption of drugs. The gastro retentive drug delivery systems retains in the stomach and assist in improving the oral sustained delivery of drugs that have an absorption window in a particular region of the gastro intestinal tract. These systems help...