01. September 2018
Flow properties of microcrystalline cellulose (MCC) excipients, Avicel PH 101 and Avicel PH 102 have been compared by using Brookfield PFT. Afterwards, the effect of hydrophobic Silica R972 as glidant has been tested on both the excipients. Hand blending is done by mixing MCCs with hydrophobic silica R972 vigorously by SAC as an underlined basis for 10 minutes and the flow properties tests are performed. During the flow function test “as received” Avicel PH 102 shows better flow function...
04. September 2016
Abstract: This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were...