17. April 2018
This article reviews various polysaccharides used in transdermal drug delivery system. The system provides continuous controlled delivery of active ingredients through human skin and into the blood stream. Poor penetration of most drugs into the skin has led to numerous studies being conducted to increase the permeability of such drugs. Currently, the interest to utilize natural polysaccharides in transdermal formulations has increased as an alternative to the synthetic materials. Structure...
13. December 2017
The vulnerability of controlled release formulations when co-ingested with alcohol represents a current major concern of regulatory agencies. Dose dumping might occur when drugs and/or excipients exhibit higher solubility in ethanolic solutions compared to water.
11. May 2017
Developed Xanthan gum based graft copolymers of Poly(N-vinyl pyrrolidone).
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Graft copolymers are cross-linked sodium alginate, which form 3 dimensional network.
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Cross-linked polymers form circular beads which loads highly soluble levofloxacin.
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Beads deliver highly soluble levofloxacin with very controlled rate at pH 7.4 & 37 °C