08. November 2017
Co-processing is currently of interest in the generation of high-functionality excipients for tablet formulation. In the present study, comparative analysis of the powder and tableting properties of three co-processed starches prepared by three different methods was carried out. The co-processed excipients consisting of maize starch (90%), acacia gum (7.5%) and colloidal silicon dioxide (2.5%) were prepared by co-dispersion (SAS-CD), co-fusion (SAS-CF) and co-granulation (SAS-CG).
27. May 2016
Objective: Shea gum is found large quantities in the northern part of Ghana. Its use in the pharmaceutical industry has been limited by lack of research into the possible uses of the gum as a pharmaceutical excipient. This study seeks to investigate the use of shea gum as a suspending agent using paracetamol as a model drug. Method: The crude shea gum was collected, purified and used as a suspending agent to formulate paracetamol suspensions using gum concentrations of 1 %w/v, 2 %w/v, 3 % w/v...