08. July 2015
Formulations of the same active pharmaceutical ingredients (API) may contain a variety of inactive pharmaceutical ingredients (IPI) or excipients. Package inserts are important sources of information to clinicians and should provide details of both the API and the excipients in the pharmaceutical preparation. The Medicine Control Council's published guidelines recommend the inclusion of excipients (qualitative) in the package insert, but this is not adequately enforced. Excipient-related...
24. April 2015
Formulations of the same active pharmaceutical ingredients (API) may contain a variety of inactive pharmaceutical ingredients (IPI) or excipients. Package inserts are important sources of information to clinicians and should provide details of both the API and the excipients in the pharmaceutical preparation... http://reference.sabinet.co.za/sa_epublication_article/caci_v28_n1_a7
25. February 2015
Newborn babies can require significant amounts of medication containing excipients intended to improve the drug formulation. Most medicines given to neonates have been developed for adults or older children and contain excipients thought to be safe in these age groups. Many excipients have been used widely in neonates without obvious adverse effects. Some excipients may be toxic in high amounts in which case they need careful risk assessment.......