30. October 2017

The purpose of this work was to investigate the effect on the dissolution behavior when silica was added in different ways. The solid dispersion was prepared by hot-melt extrusion (HME) using indomethacin (IND) as a model drug and Kollidon VA64 as a carrier.

25. October 2017

Majority of the pharmaceutical dosage forms are manufactured from powders as a starting material. The handling and processing problems in pharmaceutical manufacturing still revolves around unpredictable bulk behavior of powders in different manufacturing conditions. This work is an attempt to improve and study the particle properties and bulk behavior of some of the commonly known fine cohesive powders under varying humidity conditions through surface modification using nano-coating technique.