22. August 2017
There are many important diseases whose treatment could be improved by delivering a therapeutic protein to the colon, for example, Clostridium difficile infection, ulcerative colitis and Crohn’s Disease. The goal of this project was to investigate the feasibility of colonic delivery of proteins using multiparticulate beads.
24. January 2017
Abstract Background: Respiratory diseases are mainly derived from acute and chronic inflammation of the alveoli and bronchi. The pathophysiological mechanisms of pulmonary inflammation mainly arise from oxidative damage that could ultimately lead to acute lung injury (ALI). Apigenin (Api) is a natural polyphenol with prominent antioxidant and anti-inflammatory properties in the lung. Inhalable formulations consist of nanoparticles (NPs) have several advantages over other administration routes...
27. February 2015
Excipients are substances other than the active drug that form a vital constituent of a formulation. Albumin as an excipient has wide applications in drug formulation, drug delivery, vaccine manufacturing and as a component of media for the production of vaccines. Continue reading... http://www.europlat.org/albumin-as-a-multifunctional-excipient-a-paradigm-shift-in-drug-development-and-delivery.htm