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08. November 2016
Abstract The objective was to investigate poly vinyl acetate (Kollicoat® SR 30 D) and ammonio methacrylate copolymer (Eudragit® RL 30 D) blends as coatings to increase the mechanical robustness of hydroxypropyl methylcellulose (HPMC) matrix tablets. Poly vinyl acetate (Kollicoat® SR 30 D – KSR) was selected for its flexibility and ammonio methacrylate copolymer (Eudragit® RL 30 D – ERL) because of its high permeability. Films based on KSR:ERL blends were prepared by casting or spraying...