15. December 2016

Introduction Talc has been traditionally used as an anti-tack agent in various immediate release and enteric coating formulations. However, it is subject to sedimentation and may cause system instability. Sedimentation of talc can lead to process concerns such as gun clogging which may lead to frequent process interruptions. Objective To determine the feasibility of formulating a ready mixed immediate release coating system containing polymer, plasticizer, and a non-talc anti-adherent agent....