01. March 2018
Most of antibacterial and antiviral agents and drugs for the treatment of central nervous system and cancer are water-insoluble, which reduces their bioavailability. The bioavailability of substances can be increased by using a dosage form such as nanosuspension.
14. April 2016
In this study, the effect of the incubation time, incubation temperature, pH, metal and sodium ions on the antibacterial activity of chitosan against food borne spoilage bacteria focused. Aeromonas hydrophila and Staphylococcus aureus, were used as two food borne bacteria. Acetic acid was used dissolving of chitosan. Results showed that chitosan solution at 5 mg/mL significantly inhibited the growth of A. hydrophila and S. aureus in presence of time, pH and metal ions (p <0.01). However,...
13. August 2015
Besides the known propolis biological activities, widely reported in many scientific studies, new findings in animal models have opened new fields for propolis application. Recently, there has been an increased interest in dried extracts based on natural products including propolis, as the product in the dry presentation shows several advantages. Therefore, standardizing a more soluble dry extract and allowing the production of human dosage forms are of great interest. In this context, this...
28. April 2015
The premise of the present study was to suitably select or modify the constitution of the polymer matrix to achieve significantly high entrapment of hydrophilic drugs within polymeric nanoparticles (NPs). Glycyrrhizin (GL), the bioactive drug was selected as a representative hydrophilic drug…. http://www.sciencedirect.com/science/article/pii/S0141813015002433