18. March 2016

In this study, novel flavored taste masking film coating formulations were developed specifically for felines. Polymethacrylate copolymer (Eudragit® E) was used as an aqueous taste masking film former in different combinations with meat precursors and flavors selected on the basis of the feline carnivorous nature. Special attention was paid to the effects of flavors on the pH and colloidal characteristics of the aqueous film coating dispersions, and to the thermal behavior, mechanical strength...

20. November 2015

08. October 2015

The aim of this study was to evaluate binders to improve the flowability of granulates and compactibility of Metformin HCL (Met) using the moist aqueous granulation (MAG) process. The effect of the binder moisture content on granulate and tablet quality was also evaluated. Vinylpyrrolidone-vinyl acetate copolymer (Kollidon VA64 fine: VA64), polyvidone (Povidone K12: PVP), hydroxypropyl cellulose (HPC SSL SF: HPC) and hydroxypropyl methylcellulose (Methocel E5 LV: HPMC) were evaluated as...

26. September 2015

One of the most important obstacles to successful oral drug delivery is the poor solubility of many drugs in aqueous media. This problem is of intense scientific and practical interest, impacting the effectiveness of marketed drugs, as well as the success rate and expense of new drug development. More

22. September 2015

Praziquantel (PZQ), an anthelmintic drug used in developing countries for the treatment of schistosome infections, was processed using the fluid bed wet granulation technology to prepare fast dispersible granules, as an appropriate and flexible dosage form for pre-school-aged children. More

07. May 2015