The selection of the excipient(s) for a tablet formulation should take into account the API properties, process, target formulation and potential impact on the formulation. Some of those API properties can be Dose Particle Size Flow Properties Bulk Density Moisture Content Hygroscopicity Excipient Compatibility Compactability The following tables show some possible impacts on the tablet formulation and considerations to take into account. Pharmaexcipients.com thanks Fred Monsuur, Grace for the...
Excipients with good flowability, bulk density as well as compaction properties are desired for use in tableting since they play important roles in formulation development and processing, including, handling, mixing, feeding and compaction.