26. October 2017

Mycotoxins are secondary toxic metabolites that are produced by fungi representing threats to human and animal health. The objective of this study was to evaluate the adsorption capacity of Chitosan (CHI), and three cellulosic polymers (HPMC, CMC, and MCC), on six mycotoxins (AFB1; FUB1; OTA; T-2; DON; and, ZEA) using an in vitro digestive model for poultry. The adsorbent capacity of the materials in the supernatant of each compartment was evaluated by a non-competitive chemiluminescent assay....

21. September 2016

ABSTRACT Transdermal patch is a medicated adhesive patch that is placed on the skin to deliver the drug through the skin in order to achieve systemic absorption of drug at a predetermined rate over a prolonged period of time. The amalgamation of polymer and pharmaceutical sciences led to the introduction of polymer in the design and development of drug delivery systems. Polymeric delivery systems are mainly intended to achieve controlled or sustained drug delivery. Polysaccharides fabricated...

27. March 2016

In “The Lives of a Cell”, L. Thomas restated a hitherto prosaic observation as a profound conjecture, i.e, that mitochondria - the earliest aerobic bacteria - may have “created” us as a ‘symbiont utilitarian layer’ for their survival. The same can be argued for the bacteria resident in the gastrointestinal system which, to put it bluntly, may have ‘created’ us in order to feed them. There are more bacteria in the human body (>500 species) than there are human cells. Most of...

26. September 2015

One of the most important obstacles to successful oral drug delivery is the poor solubility of many drugs in aqueous media. This problem is of intense scientific and practical interest, impacting the effectiveness of marketed drugs, as well as the success rate and expense of new drug development. More

06. August 2015