22. February 2016

The global pharmaceutical excipients market, a multibillion market, is projected to expand at a healthy pace of 6.7 percent annually in the next five years and reach $8.4 billion by 2019 (Markets and Markets, 2015). This continued growth is largely driven by the increasing demand for pharmaceutical products to serve an aging population and improve healthcare worldwide. Despite the positive outlook, the industry itself faces a variety of challenges to meet the expectations of the regulators, end...

23. May 2015

Introduction Over 60% of new chemical entities that are poorly soluble qualify either as BCS Class II or Class IV and they provide challenges as well as opportunities to scientists working in formulation development [1]. The conventional solubilization approaches such as physical modifications of drug crystals (surface alteration of API, micronization or micro-milling) usually lead to a limited dissolution and solubility enhancement, but when developing a medium or high dosed formulation, the...