07. November 2017
This Guide is intended to provide support to both manufacturers and users of co-processed excipients. In addition, it is intended that this Guide should facilitate communication between excipient users and suppliers regarding the safety information required for regulatory filing for a product containing a novel co-processed excipient.
23. October 2017
The development of novel excipients with enhanced functionality has been explored using particle engineering by co-processing. The aim of this study was to improve the functionality of tapioca starch (TS) for direct compression by co-processing with gelatin (GEL) and colloidal silicon dioxide (CSD) in optimized proportions.
17. August 2017
For the development of this directly compressible excipient no chemical modification was applied. The enhanced functionality enabling a nearly zero order release was achieved by techniques such as physical mixing, high shear mixer granulation and spray drying.