31. March 2018

Just found this chapter of the 2nd Edition of "Pharmaceutical Extrusion Technology" which can be of interest in the field of continuous manufacturing. Hot melt extrusion (HME) is a continuous process operation that has been successfully applied to the manufacture of quality drug products over the last decade [1–4]. 54HME achieves the molecular mixing of active pharmaceutical ingredients (API) and excipients at temperatures above their glass transition temperatures (T g) and/or melting...