02. March 2016

Aim: The present work was aimed to formulate Verapamil hydrochloride (HCl) an antihypertensive agent as controlled release (CR) matrix tablets using naturally occurring hydrophobic gum such as dammar gum as a polymer. Methods: In the present investigation, an attempt was made to induce hydrogel formation using polyelectrolytes such as calcium hydroxide and sodium hydroxide with the dammar gum in the presence of dissolution media and to extend the drug release up to 12 h. The hydrogels thus...