30. October 2016

Abstract Liposomes are self-assembled bilayer vesicles which have attracted a great deal of interest as potential carriers for a wide range of therapeutic agents. They have significantly decreased toxicity of drugs while improving or at least maintaining their efficacy. However, their further development has been hampered by their considerable instabilities and, in some cases, providing comparable efficacy to conventional products. Decoration of liposomal nanocarriers with chitosan (CS) and its...

23. August 2016

Introduction Increased complications and expense involved in marketing of new drug entities has focused greater attention on development of sustained and controlled release drug delivery systems [1]. The purpose of the systems is to maintain drug concentration in the blood or in target tissues at a desired value as long as possible. To achieve predictable and reproducible release rates, extended duration of activity for short half-life drugs, decreased toxicity, and reduction of required dose,...

24. February 2016

Natural polymers and their derivatives have been widely used in pharmaceutical and food industries. The development of delivery systems using natural polymers such as gums offers distinct advantages, such as, biocompatibility, biodegradability, and cost effectiveness. Cashew gum (CG) is an exudate taken from Anacardium occidentale, which is a common tree in Braziĺs northeastern region. CG has rheological and mucoadhesive properties that can find many applications, among which the design of...