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07. September 2018
Lipid based formulations are known to enhance the solubility of drug compounds. The purpose of this study was to determine the intrinsic solubility enhancement of several drug compounds in the presence of a lipid based formulation at 37°C. The ratio of the components in the formulation were varied to investigate the effect of composition on the solubility of the compound. Conclusion Using CheqSol, it was possible to readily evaluate the solubility of ionizable compounds at elevated...