03. May 2017
The local delivery of drug to the lung can be achieved by using nebulizers, pressurized meter dose inhalers (pMDIs), or dry powder inhalers (DPIs). Among the three inhalations, DPIs offer advantages over nebulizers and pMDIs from the environmental and economical points, since they are propellant-free, portable, and stable as a result of dry state1. These advantages make DPIs particularly suited to therapeutic aerosols.
03. May 2017
• Drug-adsorbed porous polymeric adsorbents as oral sustained release formulations. •The adsorption (load) is performed in water medium without use of organic solvents. • The formulations show both sustained release and high oral bioavailability. • The release rate can be controlled by pore size of the adsorbents.
02. May 2017
The accessibility of 3D printers for both industrial and general public use has grown dramatically in the past decade. Global sales that include the devices, materials and services for industrial-scale to consumer-based printers have grown by an annual average of more than 33% over the last three years to a total of $4.1 billion in 2014. A significant driver of this growth is the fact that the early patents related to the manufacturing devices and printer processes have expired.
04. November 2016
The use of various types of printing technologies offer potential solutions for personalized medicine and tailored dosage forms to meet the needs of individual treatments of the future. Many types of scenario for printed dosage form exist and the concepts include, on the simplest level, accurately deposited doses of drug substances. In addition, computer design allows endless opportunities to create suitable geometries with tailored functionality and different levels of complexity to control...
29. June 2015
Chemists at MIT have created a triple warhead against cancer. They believe theirs is the first example a polymer nanoparticle which carries a precise ratio of three drugs that can be released in response to three distinct triggers. More
27. April 2015
Eur J Pharm Sci. 2015 Apr 20. pii: S0928-0987(15)00155-4. doi: 10.1016/j.ejps.2015.04.012. Lipocalin-type prostaglandin D synthase (L-PGDS), a member of the lipocalin superfamily, possesses the function of forming complexes together with various small lipophilic molecules. In this study, we chose telmisartan as a model drug due to its pH dependent poor water solubility, and developed and characterized a novel solubilized formulation of telmisartan using a complex formulation with L-PGDS......