04. October 2017
Filling a dosator nozzle moving into a powder bed was investigated using the Discrete Element Method (DEM). Various particle diameters and contact properties were modeled. The simulations qualitatively showed the influence of powder properties on the amount of dosed powder.
04. September 2016
Abstract The die filling process within a lab-scale rotary tablet press is simulated using the Discrete Element Method (DEM). The particle motion is captured as particles travel from the gravity feeder consisting of a chute connected to the shoe represented by a rectangular box to the dies/cavities of the turret. The particles fill the dies mostly due to gravity. The process conditions such as die table speed, die diameter as well as the material characteristics e.g. cohesion, coefficient of...
11. August 2015
Capping is one of the major problems that occur during the tabletting process in the pharmaceutical industry. This study provided an effective method for evaluating the capping tendency during diametrical compression test using the finite element method (FEM). In experiments, tablets of microcrystalline cellulose (MCC) were compacted with a single tabletting machine, and the capping tendency was determined by visual inspection of the tablet after a diametrical compression test. More